|
|
Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019
Suchopárová, Lenka ; Malý, Josef (advisor) ; Kolář, Jozef (referee)
Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019 Author: Lenka Suchopárová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Petr Domecký Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles university Introduction and aims: Antibiotics (ATB) are substances with a bacteriostatic or bactericidal effect. Treatment with ATB carries a risk of side effects, drug interactions and risk of resistance occurence. The reason for monitoring the consumption of ATB is not only the apparent coherence between their consumption and the increase of resistance, but also the economic side of bacterial infections treatment. The aim of this study was to analyze the consumption of ATB for systematic administration in the Czech Republic (CR) in 2005-2019. Methods: The analysis of the consumption of ATB was performed as a retrospective analysis of data from the database of the State Institute of Drug Control in the period from 1. 1. 2005 to 31. 12. 2019. Anatomical-therapeutic-chemical classification based on defined daily doses (DDD) of individual drugs was used for the analysis. The consumption of ATB was calculated as DDD per thousand inhabitants per day (TID). The data on the number of residents was acquired from the...
|
|
|
Analysis of drug utilization of antidiabetics
Dvořáková, Nelly ; Malý, Josef (advisor) ; Doseděl, Martin (referee)
Analysis of drug utilization of antidiabetics Author: Nelly Dvořáková Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Simona Dvořáčková, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and objective: Effects of antidiabetics prevent serious consequences on mortality, morbidity and quality of life of patients. The objective of practical part of this thesis was to analyze trends of antidiabetics utilization in the Czech Republic between 2005−2021. Methods: The utilization of antidiabetics was analysed in the period from 1st January 2005 to 31st December 2021. The data were obtained from the State Institute for Drug Control database, where are collected reports from distributors regarding the supplies to healthcare institutions including pharmacies, vendors of selected pharmaceuticals and veterinarians. The denominator was number of inhabitants in Czech Republic in particular years in study period. The drug utilization of antidiabetics in Defined Daily Doses (DDD) was converted to Defined Daily Dose/1000 inhabitants/day (DID). The values of DDD of medicaments in fixed combinations were also converted to DID but not converted to their single components. The descriptive statistics was used to analyze the data. Results:...
|
|
|
Analysis of Anticoagulant Utilization in the Czech Republic in the period from 2007 to 2016
Hochelová, Zuzana ; Zimčíková, Eva (advisor) ; Malý, Josef (referee)
Analysis of anticoagulant utilization in the Czech republic in the period from 2007 to 2016 Author: Zuzana Hochelová1 Supervisor: PharmDr. Eva Zimčíková, Ph.D.1 Consultant: PharmDr. Kateřina Malá, Ph.D.1 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction: Anticoagulants are drugs that reduce blood clotting and prevent the formation of blood clots. In the Czech Republic - antagonists of vitamin K-warfarin, direct oral inhibitors of factor Xa-rivaroxaban, apixaban, edoxaban, direct oral inhibitors trombin - dabigatran, parenteral anticoagulants - heparin, low-molecular heparin, fondaparinux, oral and parenteral hirudin are used. Objective: The objective of this diploma thesis was to assess the consumption of oral and parenteral anticoagulants in the Czech Republic from 01. 01. 2007 to 31. 12. 2016, based on the data from the State Institute of Drug Control (SIDC). Methods: ATC/DDD methodology was applied. The research consisted of a retrospective analysis of the SIDC database. All oral and parental anticoagulants approved in the CR were included in the study. Drug utilization was calculated as number of defined daily doses per thousands of inhabitants per day (DID). The data on the number of residents was acquired from...
|
|
|
Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019
Suchopárová, Lenka ; Malý, Josef (advisor) ; Kolář, Jozef (referee)
Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019 Author: Lenka Suchopárová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Petr Domecký Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles university Introduction and aims: Antibiotics (ATB) are substances with a bacteriostatic or bactericidal effect. Treatment with ATB carries a risk of side effects, drug interactions and risk of resistance occurence. The reason for monitoring the consumption of ATB is not only the apparent coherence between their consumption and the increase of resistance, but also the economic side of bacterial infections treatment. The aim of this study was to analyze the consumption of ATB for systematic administration in the Czech Republic (CR) in 2005-2019. Methods: The analysis of the consumption of ATB was performed as a retrospective analysis of data from the database of the State Institute of Drug Control in the period from 1. 1. 2005 to 31. 12. 2019. Anatomical-therapeutic-chemical classification based on defined daily doses (DDD) of individual drugs was used for the analysis. The consumption of ATB was calculated as DDD per thousand inhabitants per day (TID). The data on the number of residents was acquired from the...
|
|
|
Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019
Suchopárová, Lenka ; Malý, Josef (advisor) ; Kolář, Jozef (referee)
Analysis of drug utilization of antibiotics for systematic administration in the Czech Republic in 2005-2019 Author: Lenka Suchopárová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Petr Domecký Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles university Introduction and aims: Antibiotics (ATB) are substances with a bacteriostatic or bactericidal effect. Treatment with ATB carries a risk of side effects, drug interactions and risk of resistance occurence. The reason for monitoring the consumption of ATB is not only the apparent coherence between their consumption and the increase of resistance, but also the economic side of bacterial infections treatment. The aim of this study was to analyze the consumption of ATB for systematic administration in the Czech Republic (CR) in 2005-2019. Methods: The analysis of the consumption of ATB was performed as a retrospective analysis of data from the database of the State Institute of Drug Control in the period from 1. 1. 2005 to 31. 12. 2019. Anatomical-therapeutic-chemical classification based on defined daily doses (DDD) of individual drugs was used for the analysis. The consumption of ATB was calculated as DDD per thousand inhabitants per day (TID). The data on the number of residents was acquired from the...
|
|
|
Analysis of Anticoagulant Utilization in the Czech Republic in the period from 2007 to 2016
Hochelová, Zuzana ; Zimčíková, Eva (advisor) ; Malý, Josef (referee)
Analysis of anticoagulant utilization in the Czech republic in the period from 2007 to 2016 Author: Zuzana Hochelová1 Supervisor: PharmDr. Eva Zimčíková, Ph.D.1 Consultant: PharmDr. Kateřina Malá, Ph.D.1 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction: Anticoagulants are drugs that reduce blood clotting and prevent the formation of blood clots. In the Czech Republic - antagonists of vitamin K-warfarin, direct oral inhibitors of factor Xa-rivaroxaban, apixaban, edoxaban, direct oral inhibitors trombin - dabigatran, parenteral anticoagulants - heparin, low-molecular heparin, fondaparinux, oral and parenteral hirudin are used. Objective: The objective of this diploma thesis was to assess the consumption of oral and parenteral anticoagulants in the Czech Republic from 01. 01. 2007 to 31. 12. 2016, based on the data from the State Institute of Drug Control (SIDC). Methods: ATC/DDD methodology was applied. The research consisted of a retrospective analysis of the SIDC database. All oral and parental anticoagulants approved in the CR were included in the study. Drug utilization was calculated as number of defined daily doses per thousands of inhabitants per day (DID). The data on the number of residents was acquired from...
|
|
|
Analysis of Anticoagulant Utilization in the Czech Republic in the period from 2007 to 2016
Hochelová, Zuzana ; Zimčíková, Eva (advisor) ; Malý, Josef (referee)
Analysis of anticoagulant utilization in the Czech republic in the period from 2007 to 2016 Author: Zuzana Hochelová1 Supervisor: PharmDr. Eva Zimčíková, Ph.D.1 Consultant: PharmDr. Kateřina Malá, Ph.D.1 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction: Anticoagulants are drugs that reduce blood clotting and prevent the formation of blood clots. In the Czech Republic - antagonists of vitamin K-warfarin, direct oral inhibitors of factor Xa-rivaroxaban, apixaban, edoxaban, direct oral inhibitors trombin - dabigatran, parenteral anticoagulants - heparin, low-molecular heparin, fondaparinux, oral and parenteral hirudin are used. Objective: The objective of this diploma thesis was to assess the consumption of oral and parenteral anticoagulants in the Czech Republic from 01. 01. 2007 to 31. 12. 2016, based on the data from the State Institute of Drug Control (SIDC). Methods: ATC/DDD methodology was applied. The research consisted of a retrospective analysis of the SIDC database. All oral and parental anticoagulants approved in the CR were included in the study. Drug utilization was calculated as number of defined daily doses per thousands of inhabitants per day (DID). The data on the number of residents was acquired from...
|
guest ::
